Inhibition of Nuclear Transport of Caspase-7 by Its Prodomain
نویسندگان
چکیده
منابع مشابه
The Inhibition of the Nuclear Transport of Caspase-7 by its Prodomain
Apoptosis is a major form of cell death, characterized by a series of the morphological changes induced by cleaving cytoplasmic and nuclear proteins via active caspases. The data presented here show, by the fluorescence microscopic and the immunoblotting analyses, that a prodomain of caspase-7 inhibits its nuclear translocation and apoptosis-inducing activity. This nuclear localization is depen...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2002
ISSN: 0006-291X
DOI: 10.1006/bbrc.2002.6408